Author

D. Petrovic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 3 Assay:proteomics· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. Gamiz-Arco· 2 shared M. Filipovic· 2 shared A. Katsouda· 1 shared A. Longchamp· 1 shared A. Papapetropoulos· 1 shared A. Romero-Rivera· 1 shared B. Ibarra-Molero· 1 shared B. Seelig· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

G. Gamiz-Arco

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ancestral versus Modern Substrate Scope in Family-1 Glycosidases

L. I. Gutierrez-Rus, D. Petrovic, P. Schneider, K. Zorn, G. Gamiz-Arco, R. Romero-Zaliz, I. Suarez-Martin, L. De Maria, F. Falcioni, V. A. Risso, M. A. Hayes, J. M. Sanchez-Ruiz

This study compares the substrate scope of a modern and ancestral family-1 glycosidase, finding the ancestral enzyme more efficient with large aglycon-containing flavonoid glycosides.

bioRxiv · Apr 11, 2024Biochemistry

Protein thiol alterations drive aberrant phase separation in aging

T. Vignane, M. Hugo, C. Hoffmann, A. Katsouda, J. Petric, H. Wang, M. Miler, F. Comas, D. Petrovic, S. Chen, J. L. Miljkovic, J. L. Morris, S. R. Chowdury, J. Prudent, N. Polovic, , M. Filipovic

This study shows that aging-related changes in cysteine posttranslational modifications alter protein phase separation, leading to aggregation and neurodegeneration.

bioRxiv · Nov 7, 2023 · PreprintBiochemistry

ATF-4 and hydrogen sulfide signalling mediate longevity from inhibition of translation or mTORC1

C. Statzer, J. Meng, R. Venz, M. Bland, S. Robida-Stubbs, K. Patel, D. Petrovic, R. Emsley, P. Liu, I. Morantte, C. Haynes, W. B. Mair, A. Longchamp, M. Filipovic, T. K. Blackwell, C. Y. Ewald

The paper shows that ATF-4 and hydrogen sulfide signaling mediate longevity from translation or mTORC1 inhibition in C. elegans.

bioRxiv · Nov 2, 2020 · PreprintPhysiology

Novel heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase

G. Gamiz-Arco, L. Gutierrez-Rus, V. Risso, B. Ibarra-Molero, Y. Hoshino, D. Petrovic, A. Romero-Rivera, B. Seelig, J. Gavira, S. Kamerlin, E. Gaucher, J. Sanchez-Ruiz

This study identifies a heme-binding site in an ancestral glycosidase, showing how heme binding rigidifies the TIM-barrel and enhances catalysis.

bioRxiv · May 27, 2020Biophysics