Morphine-induced side effects can be differentially modulated by cannabidiol in male and female rats.
C. H. A. Jesus, J. Volpe, B. B. Sotomaior, M. A. R. Barbosa, M. V. Ferreira, F. Fiatcoski, K. Genaro, J. A. d. S. Crippa, D. E. P. Souto, J. M. da Cunha
This study shows that cannabidiol reduces morphine-induced hyperalgesia and withdrawal signs in rats, with sex-dependent effects on withdrawal behaviors.
bioRxiv · Jan 22, 2024 · PreprintPharmacology & Toxicology