Physicochemical Properties of Chromosomes in Live Cells Characterized by Label-Free Imaging and Fluorescence Correlation Spectroscopy
T.-K. Kim, B.-W. Lee, F. Fujii, K.-H. Lee, Y. Park, J. K. Kim, C.-G. Pack
The paper quantifies physicochemical properties of mitotic chromosomes in live cells using label-free imaging and fluorescence correlation spectroscopy, showing correlations between refractive index, volume, and protein mobility under osmotic changes.
bioRxiv · Jan 29, 2019 · PreprintBiophysics