PTEN inhibits AMPK to control collective migration
F. PEGLION, L. Capuana, I. Perfettini, B. braithwaite, F. Llense, E. Quissac, K. Forsberg-Nilsson, s. Etienne-Manneville
This study shows that PTEN loss increases collective cell migration by enhancing AMPK activity, which weakens cell-cell contacts and promotes invasion in glioblastoma.
bioRxiv · Dec 13, 2021Cell Biology