Assessment of chemotherapy-induced organ damage with 68Ga-labeled duramycin
A. Rix, N. I. Drude, A. Mrugalla, F. Baskaya, K. Y. Pak, B. Gray, H.-J. Kaiser, R. H. Tolba, E. Fiegle, W. Lederle, F. M. Mottaghy, F. Kiessling
This paper evaluates [68Ga]Ga-NODAGA-duramycin as a PET tracer for detecting chemotherapy-induced organ toxicity in mice, showing it can identify toxic effects earlier than blood tests and histology.
bioRxiv · May 17, 2019Pharmacology & Toxicology