Author

F. Markwardt

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Biophysics· 1

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Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:Xenopus· 1

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A. S. Malisetty· 1 shared E. Schoen· 1 shared G. Schmalzing· 1 shared M. Berthold· 1 shared M. Raycheva· 1 shared S. Hawro Yakoob· 1 shared

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2024-2024 · peak 1/yr

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A. S. Malisetty

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1 paper

Recent·Most cited

Two serial filters determine P2X7R cation selectivity, Ser342 in the central pore and lateral acidic residues at the cytoplasmic interface

F. Markwardt, E. Schoen, M. Raycheva, A. S. Malisetty, S. Hawro Yakoob, M. Berthold, G. Schmalzing

This paper identifies two sequential filters in the P2X7R channel that determine cation selectivity: a dynamic tri-serine-342 size filter and static acidic residues at the cytoplasmic interface.

bioRxiv · Feb 19, 2024 · PreprintBiophysics