Poly(ADP-ribose)-binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions
R. R. Kumbhar, J. Perren, F. Gong, D. Corujo, F. Medina, A. Matouschek, M. Buschbeck, K. M. Miller
This study identifies PAR-binding and macroH2A1.2 as factors that mediate KDM5A recruitment to DNA damage sites, enhancing its repair and transcriptional functions at chromatin breaks.
bioRxiv · Jul 27, 2020Cell Biology