Cardiomyocyte-specific ACSL1 Deficiency Prevents Cardiac Lipotoxicity and Alleviates Heart Dysfunction in the ob/ob Model of Obesity
F. Pascual, T. J. Grevengoed, L. Zhao, M. S. Willis, R. A. Coleman
This study shows that reducing ACSL1 in cardiomyocytes prevents lipotoxicity and improves heart function in obese mice.
bioRxiv · Jan 24, 2020 · PreprintPhysiology