Author

R. A. Coleman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

R. H. Singer· 2 shared W.-L. Liu· 2 shared A. Piasecka· 1 shared A. Senecal· 1 shared C. A. Kenworthy· 1 shared C. M. So· 1 shared C. S. Peng· 1 shared E. L. Klett· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

R. H. Singer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Perilipin 5 interacts with Fatp4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport

G. E. Miner, C. M. So, W. Edwards, L. E. Herring, R. A. Coleman, E. L. Klett, S. Cohen

This study identifies Plin5 and Fatp4 interaction at LD-mitochondria contacts, showing phosphorylation of Plin5 and Fatp4's role in fatty acid transport during starvation.

bioRxiv · Feb 3, 2022Cell Biology

Bromodomains regulate dynamic targeting of the PBAF chromatin remodeling complex to chromatin hubs

C. A. Kenworthy, N. Haque, S.-H. Liou, P. Chandris, V. Wong, P. Dziuba, L. D. Lavis, W.-L. Liu, R. H. Singer, R. A. Coleman

This study uses live-cell imaging to show that PBAF chromatin remodeler dynamically targets acetylated chromatin hubs via bromodomains, with distinct binding kinetics in euchromatin and heterochromatin.

bioRxiv · Nov 2, 2021Cell Biology

Transcriptional burst kinetics are linked to short term transcriptional memory

A. Senecal, R. H. Singer, R. A. Coleman

The paper studies transcriptional bursting at the p21 gene and identifies short-term transcriptional memory (STTM) linked to p53 regulation and burst duration.

bioRxiv · Oct 31, 2021 · PreprintCell Biology

Cardiomyocyte-specific ACSL1 Deficiency Prevents Cardiac Lipotoxicity and Alleviates Heart Dysfunction in the ob/ob Model of Obesity

F. Pascual, T. J. Grevengoed, L. Zhao, M. S. Willis, R. A. Coleman

This study shows that reducing ACSL1 in cardiomyocytes prevents lipotoxicity and improves heart function in obese mice.

bioRxiv · Jan 24, 2020 · PreprintPhysiology

p53 dynamically directs TFIID assembly on target gene promoters

R. A. Coleman, Z. Qiao, S. K. Singh, C. S. Peng, M. Cianfrocco, Z. Zhang, A. Piasecka, H. Aldeborgh, G. Basishvili, W.-L. Liu

This study shows p53 dynamically facilitates TFIID assembly on target promoters through DNA binding and conformational changes.

bioRxiv · Feb 24, 2017Biochemistry