Screening megasynthetase mutants at high throughput using droplet microfluidics
F. Pourmasoumi, S. Hengoju, K. Beck, P. Stephan, L. Klopfleisch, M. Hoernke, M. A. Rosenbaum, H. Kries
The paper develops a microfluidic platform to screen NRPS mutants for antibiotic production, achieving significant enrichment of active variants.
bioRxiv · Jan 13, 2023 · PreprintBioengineering