Proteogenomic analysis reveals RNA as an important source for tumor-agnostic neoantigen identification correlating with T-cell infiltration
C. Tretter, N. de Andrade Kraetzig, M. Pecoraro, S. Lange, P. Seifert, C. von Frankenberg, J. Untch, F. S. Dreyer, E. Braeunlein, M. Wilhelm, D. P. Zolg, T. Engleitner, S. Uhrig, M. Boxberg, K. Steiger, , A. M. Krackhardt
This study identifies RNA as a significant source of tumor-agnostic neoantigens, which correlate with T-cell infiltration in multiple cancer types.
bioRxiv · Sep 17, 2022Cancer Biology