Genetic Loss of Nicotinamide Nucleotide Transhydrogenase Prevents from Cardiometabolic Heart Failure with Preserved Ejection Fraction
M. E. Pepin, S. Nazir, P. J. M. Konrad, F. Schreiter, M. Dewenter, J. Backs
This study shows that genetic loss of NNT protects mice from cardiometabolic heart failure with preserved ejection fraction caused by HFD+L-NAME, with sex-specific effects.
bioRxiv · Apr 21, 2023 · PreprintPhysiology