Author

F. Segovia-Miranda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:imaging· 3 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Research Focus:spatial domain detection· 2 Approach:statistical model· 2 Approach:deep learning· 1 Organism:mouse· 1

Frequent Co-Authors

M. Zerial· 4 shared H. Morales-Navarrete· 3 shared Y. Kalaidzidis· 3 shared L. Brusch· 2 shared A. Hendriks· 1 shared A. Scholich· 1 shared B. M. Friedrich· 1 shared C. Perez· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersCell Biology

M. Zerial

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Hep3D: A 3D single-cell digital atlas of the liver to study spatio-temporal tissue architecture

D. Martinez, V. Maldonado, C. Perez, R. Yanez, V. Candia, Y. Kalaidzidis, M. Zerial, H. Morales-Navarrete, F. Segovia-Miranda

The paper develops Hep3D, a 3D single-cell atlas of the mouse liver, revealing spatiotemporal patterns of cellular structures and the structural role of Kupffer cells in liver homeostasis.

bioRxiv · Jan 21, 2023 · PreprintCell Biology

Bridging scales in scattering tissues via multifocal two-photon microscopy

D. Chen, F. Segovia-Miranda, N. Walker, J. I. Valenzuela, M. Zerial, E. W. Myers

This paper introduces multifocal two-photon microscopy to image mesoscopic scattering tissues at high resolution and speed without tissue-clearing methods.

bioRxiv · Jun 11, 2020 · PreprintBioengineering

3D spatially-resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression

F. Segovia-Miranda, H. Morales-Navarrete, M. Kucken, V. Moser, S. Seifert, U. Repnik, F. Rost, A. Hendriks, S. Hinz, C. Rocken, D. Luthjohann, Y. Kalaidzidis, C. Schafmayer, L. Brusch, J. Hampe, M. Zerial

This study creates 3D spatial models of human liver tissue to identify new morphometric parameters and topological defects linked to NAFLD progression.

bioRxiv · Mar 9, 2019Pathology

Liquid-crystal organization of liver tissue

H. Morales-Navarrete, H. Nonaka, A. Scholich, F. Segovia-Miranda, W. de Back, K. Meyer, R. L. Bogorad, V. Koteliansky, L. Brusch, Y. Kalaidzidis, F. Julicher, B. M. Friedrich, M. Zerial

The paper reveals that hepatocytes in liver tissue follow a long-range liquid-crystal order, challenging the traditional view of random organization and highlighting bi-directional communication between hepatocytes and sinusoids.

bioRxiv · Dec 13, 2018Biophysics