ImmunologybioRxivPreprint
Autoantibodies against Progranulin and IL-1 receptor antagonist due to immunogenic posttranslational isoforms contribute to hyperinflammation in critically ill COVID-19
L. Thurner, N. Fadle, M. Bewarder…·S. Koerper
This study identifies autoantibodies against PGRN and IL-1-Ra in critical COVID-19 patients, linked to hyperphosphorylated isoforms and increased inflammation.
DOI 10.1101/2021.04.23.441188