Structural basis for ATP-driven double-ring assembly of the human mitochondrial Hsp60 chaperonin
Igor Tascón, Jorge Pedro López-Alonso, Yoel Shkolnisky, David Gil‐Carton, Jesus Vilchez-Garcia, Alberto G. Berruezo, Yacob Gómez-Llorente, Radhika Malik, Fady Jebara, Malay Patra, Joel A. Hirsch, Abdussalam Azem, Iban Ubarretxena‐Belandia
The paper presents cryo-EM structures of human mitochondrial Hsp60 chaperonin in different states to elucidate the structural basis of ATP-driven double-ring assembly.
bioRxiv · Oct 4, 2025 · PreprintBiophysics