Author

Famke Pelser

Leiden University

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Kanwal KayasthaiD· 1 shared Lars J. C. JeukeniD· 1 shared Steffen BrünleiD· 1 shared Tijn T. van der VeldeniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Kanwal KayasthaORCID

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1 paper

Recent·Most cited

Visualizing the mechanism of quinol oxidation and inhibition of a bd-type oxidase using cryo-EM

Tijn T. van der Velden, Kanwal Kayastha, Famke Pelser, Steffen Brünle, Lars J. C. Jeuken

The paper presents cryo-EM structures of Escherichia coli cytochrome bd-I to elucidate its mechanism of quinol oxidation and inhibition, identifying key residues and structural changes involved in catalysis and drug binding.

Science Advances · May 20, 2026Peer-reviewedBiochemistry