Super-Resolved Single Small Extracellular Vesicle Assay enabled by a Plasmonic Nanohole Array
Anthony James El-helou, Liu Y, Fatemeh Khosravi, Chaohao Chen, Carol H.W Yan, Mark Lockrey, Juanfang Ruan, Zhaowei Liu, Peter John Reece, Ying Zhu
This paper introduces a nanoplasmonic platform for high-resolution single small extracellular vesicle quantification and subpopulation differentiation, achieving a detection limit of 143 sEVs/μL.
bioRxiv · Jun 16, 2026 · PreprintBioengineering