Absence of CDK12 in oocyte leads to female infertility
Denisa Jansová, Veronika Sedmikova, Fatima J. Berro, Daria Aleshkina, Michal Dvoran, Michal Kubelka, Jitka Rezacova, Jana Rutarova, Jiří Kohoutek, Andrej Šušor
This study shows that CDK12 absence in oocytes causes female infertility by disrupting transcriptional activity and maternal transcriptome maintenance.
Cell Death and Disease · Mar 27, 2025Peer-reviewedDevelopmental Biology