Andrej Šušor

This study shows pancreatic cancer cells use tunnelling nanotubes to transfer ribosomes and mRNAs, restoring protein synthesis in cells with impaired translation.

This study investigates mRNA translation dynamics during mouse pre-implantation development, revealing novel mechanisms of translational selectivity and the role of Eif1ad3 in ribosome biogenesis.

This study shows that CDK12 absence in oocytes causes female infertility by disrupting transcriptional activity and maternal transcriptome maintenance.

The paper identifies mTORC1 and 7mG-cap dependent translation as regulators of spatial positioning of blastomeres during the 8- to 16-cell transition in mouse embryos.

This study uses low-input ribosome profiling to analyze translational selectivity in bovine oocytes and preimplantation embryos, revealing four modes of translational regulation and their temporal dynamics.

This study shows that the Hira complex is essential for oocyte developmental competence by maintaining transcriptional silencing through H3.3 deposition and chromatin modifications.

This study identifies Tdrd3 as a regulator of meiosis II in mouse oocytes by controlling Emi2 mRNA translation, ensuring proper MII spindle formation.

This study shows that p38-MAPK regulates PrE differentiation during mouse blastocyst maturation by controlling translation and rRNA processing through Mybpp1a.

This study identifies Wwc2 as a regulator of cell division during mouse preimplantation embryo development and oogenesis, showing its role in maintaining cell number and division fidelity.

The paper shows that p38-MAPK regulates blastocyst development in response to amino acid availability and oxidative stress, affecting cell lineage specification and blastocyst size.