Essential genes are dominantly activated by single transcription factors
Martina Capriati, Sylke Nestmann, Izlem Su Akan, Faustus Tuschmann, Silke Druffel‐Augustin, Ralph Stefan Grand
The paper shows that single transcription factors dominantly activate essential genes through regulatory dominance rather than cooperation in murine stem cells.
bioRxiv · Apr 30, 2026 · PreprintMolecular Biology