Federico G. Gnazzo

Striatal signaling tracks naturalistic short-term fluctuations in hunger-satiety

This study examines how dopamine signaling in the nucleus accumbens changes during naturalistic feeding, showing transient increases during food approach that diminish with ingestion and recover between meals.

Accumbal Dopamine and Acetylcholine Dynamics during Psychostimulant Sensitization

This study investigates how dopamine and acetylcholine dynamics in the nucleus accumbens change with repeated psychostimulant exposure and finds that D2 receptor signaling on cholinergic interneurons is critical for sensitization of neural responses but not for behavioral sensitization.

Dietary regulation of silent synapses in the dorsolateral striatum

This study shows that dietary-induced obesity increases silent synapses in the dorsolateral striatum, similar to drugs of abuse, suggesting shared mechanisms in neural circuit remodeling.