Retrotransposon LINE1 trans-regulatory differentiation process maintain embryonic stem cell identity
Likun Ren, Yue Teng, Wenqiu Xu, Jingya Hou, Mengyue Lu, Feitong Shi, Jie Ren, Caihong Zheng, Jun Cai
This study identifies LINE1 RNA's trans-regulatory roles in maintaining ESC identity through distinct mechanisms in differentiation and 2C-like cell processes.
bioRxiv · Dec 2, 2024 · PreprintGenomics