Genomic analysis of response to neoadjuvant chemotherapy in esophageal adenocarcinoma
Fereshteh Izadi, Benjamin P. Sharpe, Stella Panagio Breininger, Maria Secrier, Jane Gibson, Robert Walker, Saqib Rahman, Ginny Devonshire, Megan A. Lloyd, Zoë S. Walters, Rebecca Claire Fitzgerald, Matthew J.J. Rose-Zerilli, Tim Underwood
This study identifies genomic features associated with response to neoadjuvant chemotherapy in esophageal adenocarcinoma, finding lower mutation burden and specific copy number alterations linked to resistance.
bioRxiv · Mar 26, 2021 · PreprintGenomics