Matthew J.J. Rose-Zerilli

Spatiotemporal dynamics of human microglia are linked with brain developmental processes across the lifespan

This study examines microglial dynamics across the human lifespan using postmortem tissues and RNAseq data, revealing novel developmental patterns linked to neurodevelopmental milestones.

Genomic analysis of response to neoadjuvant chemotherapy in esophageal adenocarcinoma

This study identifies genomic features associated with response to neoadjuvant chemotherapy in esophageal adenocarcinoma, finding lower mutation burden and specific copy number alterations linked to resistance.

Mapping biology from mouse to man using transfer learning

This paper uses transfer learning to map biology from mouse to human bone marrow using single-cell RNA-sequencing data, showing improved accuracy with retraining and zero-shot learning.