Comprehensive Whole Genome Sequencing Reveals Origins of Mutational Signatures Associated with Aging and Temozolomide Chemotherapy
Taejoo Hwang, Lukasz Karol Sitko, Ratih Khoirunnisa, Fernanda Navarro Aguad, David M Samuel, Hajoong Park, Banyoon Cheon, Luthfiyyah Mutsnaini, Jaewoong Lee, Shunichi Takeda, Semin Lee, Dmitri Ivanov, Anton Gartner
The paper analyzes whole-genome sequencing data from DNA repair-deficient cell lines to identify mutational signatures linked to aging and temozolomide chemotherapy.
bioRxiv · Apr 17, 2024 · PreprintGenomics