In vitro FLASH irradiation of A549 lung cancer cells and IMR90 healthy human fibroblasts in the synchrocyclotron room of a clinical proton therapy system
Adrián Zazpe, Inés del Monte-García, Nerea Palao, Fernando Cerrón, Mateo Cueto‐Remacha, Paula Linzoain-Agos, Minerva Iniesta‐González, Martina Quartieri, Ángel M. Cuesta, Samuel España, Guillermo Velasco, Juan Antonio Vera Sanchez, L. M. Fraile, A. Mazal, José Manuel Udías, , Daniel Sanchez Parcerisa
This study investigates FLASH irradiation effects on lung cancer and healthy fibroblast cells using a clinical proton therapy setup, finding no significant survival differences but altered cell cycle dynamics.
bioRxiv · Nov 13, 2024 · PreprintBioengineering