Álvaro Gutiérrez-Uzquiza

Demonstration of SLU7 as a new pan-cancer target

This paper identifies SLU7 as a pan-cancer target, showing its knockdown induces genomic instability and enhances immunogenicity, with effective tumor suppression in murine models.

CRISPR screening reveals SYCP3 as a key driver of metastasis in prostate cancer

This study identifies SYCP3 as a driver of prostate cancer metastasis through CRISPR screening and shows its role in invasion, adhesion, and radiotherapy resistance.

Purinergic Receptor P2Y13 Controls Activation and Mode of Division in Subependymal Adult Neural Stem Cells

This study identifies P2Y13 as a key regulator of NSC activation and division mode in the adult SEZ, distinguishing quiescent from activated NSCs and influencing self-renewal versus differentiation.

In vitro FLASH irradiation of A549 lung cancer cells and IMR90 healthy human fibroblasts in the synchrocyclotron room of a clinical proton therapy system

This study investigates FLASH irradiation effects on lung cancer and healthy fibroblast cells using a clinical proton therapy setup, finding no significant survival differences but altered cell cycle dynamics.