Regulatable In Vivo Gene Expression via Adaptamers
Jack Bryant, Laura Herron, Yesh Doctor, Finn McRae, Jocelyn Wang, Theodore Hirsch, Andrew J. Portell, Satheesh Kumar, Prashant Mali
This paper introduces an RNA-based system called adaptamer that allows precise, reversible control of gene expression using small molecules, demonstrating its function in cell lines and mice.
bioRxiv · Dec 22, 2025 · PreprintSynthetic Biology