Microglial TNFα orchestrates brain phosphorylation during the sleep period and controls homeostatic sleep.
Maria J. Pinto, Léa Cottin, Florent Dingli, Victor Laigle, Luís F. Ribeiro, Antoine Triller, Fiona J Henderson, Damarys Loew, Véronique Fabre, Alain Bessis
This study shows microglial TNFα regulates brain phosphorylation during sleep, affecting sleep need and duration through synaptic proteins.
bioRxiv · Mar 24, 2022 · PreprintNeuroscience