Impaired autophagic flux in skeletal muscle of plectin-related epidermolysis bullosa simplex with muscular dystrophy
Michaela M. Zrelski, Margret Eckhard, Petra Fichtinger, Sabrina Hösele, Andy Sombke, Leonid Mill, Monika Kustermann, Wolfgang M. Schmidt, Fiona Norwood, Ursula M. Schlötzer-Schrehardt, Gerhard Wiche, Rolf Schröder, Lilli Winter
This study identifies impaired autophagic flux in skeletal muscle of EBS-MD patients and plectin-deficient models, linking it to protein aggregation pathology.
Journal of Cachexia Sarcopenia and Muscle · Jul 10, 2025Peer-reviewedCell Biology