Cytoplasmic localization of 5hmC reveals RNA hydroxymethylation in breast cancer
Jinrui Wen, Lisa Del Bel Belluz, Silvia Ottaviani, Fotini Poyia, Hemeng Yu, Saachi Sachdev, Liliane El Eid, Katherine Garner, Krina Mistry, Emily Hayes, Nina Moderau, Pramodh Chitral Chandrasinghe, Justin Stebbing, Biancastella Cereser
The paper identifies cytoplasmic 5hmC in breast cancer tissues and cell lines, linking it to TET3 expression and RNA processing, with implications for triple-negative breast cancer.
bioRxiv · Oct 23, 2026 · PreprintCancer Biology