Author

Silvia Ottaviani

Imperial College LondonORCID 0000-0002-8830-9947Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Justin StebbingiD· 2 shared Aleksandra Dabrowska· 1 shared Biancastella CereseriD· 1 shared Emily HayesiD· 1 shared Fotini Poyia· 1 shared Hemeng YuiD· 1 shared Jinrui Wen· 1 shared Katherine GarneriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Justin StebbingORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cytoplasmic localization of 5hmC reveals RNA hydroxymethylation in breast cancer

Jinrui Wen, Lisa Del Bel Belluz, Silvia Ottaviani, Fotini Poyia, Hemeng Yu, Saachi Sachdev, Liliane El Eid, Katherine Garner, Krina Mistry, Emily Hayes, Nina Moderau, Pramodh Chitral Chandrasinghe, Justin Stebbing, Biancastella Cereser

The paper identifies cytoplasmic 5hmC in breast cancer tissues and cell lines, linking it to TET3 expression and RNA processing, with implications for triple-negative breast cancer.

bioRxiv · Oct 23, 2026 · PreprintCancer Biology

Single-cell transcriptomics uncovers that cell-to-cell communication controls p53 activation

Leandro Castellano, Mark E. Robinson, Aleksandra Dabrowska, Niklas Feldhahn, Silvia Ottaviani, Justin Stebbing

The paper uses single-cell RNA sequencing to show that cell-to-cell communication enhances p53 activation in response to chemotherapy, revealing a role for paracrine signaling in treatment response.

bioRxiv · May 30, 2025 · PreprintCancer Biology