Author

Frances C. Shaffo

F. Hoffmann-La Roche AG

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alberto ValdeolivasiD· 1 shared Ali NowrouziiD· 1 shared Bettina AmbergiD· 1 shared Björn JacobseniD· 1 shared David M. MarkusiciD· 1 shared Fabian Köchl· 1 shared Filip Bochner· 1 shared Hélène HaegeliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alberto ValdeolivasORCID

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1 paper

Recent·Most cited

Spatial Transcriptomics and Single-Nucleus RNA Sequencing Reveal rAAV2- and rAAV9-Specific Transduction Signatures in the Mouse Liver

Bettina Amberg, Fabian Köchl, Nadine Kumpesa, Megana K. Prasad, Filip Bochner, Mar Hernandez-Obiols, Michael B. Otteneder, Lucas Stalder, Frances C. Shaffo, Ali Nowrouzi, David M. Markusic, Hélène Haegel, Rebecca Xicluna, Marc Sultan, Björn Jacobsen, , Kerstin Hahn

This study uses spatial transcriptomics and single-nucleus RNA sequencing to analyze rAAV2 and rAAV9 vector effects in mouse livers, revealing sex-specific transcriptomic changes and novel transgene co-expression factors.

Gene Therapy · Mar 11, 2026Peer-reviewedMolecular Biology