Molecular BiologyGene TherapyPeer-reviewed
Spatial Transcriptomics and Single-Nucleus RNA Sequencing Reveal rAAV2- and rAAV9-Specific Transduction Signatures in the Mouse Liver
Bettina Amberg, Fabian Köchl, Nadine Kumpesa…·Kerstin Hahn
This study uses spatial transcriptomics and single-nucleus RNA sequencing to analyze rAAV2 and rAAV9 vector effects in mouse livers, revealing sex-specific transcriptomic changes and novel transgene co-expression factors.