IL-21 Shapes the B Cell Response in a Context-Dependent Manner
Youngjun Kim, Francesca Manara, Simon A. Grassmann, Kalina T. Belcheva, Kanelly Reyes, Hyunu Kim, Stephanie Downs‐Canner, William T. Yewdell, Joseph Chai-Yuen Sun, Jayanta Chaudhuri
This study reveals that IL-21 regulates B cell fate through context-dependent effects on apoptosis and proliferation, using a conditional knock-out model and ex vivo cultures.
Cell Reports · Jan 1, 2025Peer-reviewedImmunology