MicrobiologybioRxivPreprint
Within-host evolution of an avirulent Salmonella vaccine strain reveals regulatory tuning of virulence functionality without loss of function
Laëtitia I. Le Caous, Disha Tandon, Olivier P. Schären…·Siegfried Hapfelmeier
This study tracks within-host evolution of an avirulent Salmonella vaccine strain and finds that regulatory tuning of the BarA/SirA system reduces SPI-1ON cells without losing SPI-1 function.
DOI 10.64898/2026.11.10.765621