α-synuclein in the retina leads to degeneration of dopamine amacrine cells impairing vision
Elena Marrocco, Federica Esposito, Valeria Tarallo, Carboncino Anna, Filomena Grazia Alvino, Sandro De Falco, Franco Brunella, De Risi Maria, Alessia Indrieri, Surace Enrico Maria, E. De Leonibus
This study shows that overexpressing α-synuclein in the retina causes dopamine amacrine cell loss and visual impairment, which can be rescued by L-DOPA.
bioRxiv · Sep 8, 2019 · PreprintNeuroscience