Filomena Grazia Alvino

Endogenous oxytocin reconfigures brainwide network dynamics toward salience-related states

This study shows that endogenous oxytocin alters brain network dynamics, increasing salience-related network states and decreasing sensory-dominated states in mice.

Functional specialization of the hippocampus along its dorso-ventral axis: from span to supraspan in working memory capacity

This study establishes a rodent model of supraspan memory and shows that dorsal hippocampus supports high-load memory while ventral hippocampus supports egocentric strategies.

Cortical excitability inversely modulates fMRI connectivity via low-frequency neuronal coupling

The paper shows that cortical excitability inversely affects fMRI connectivity, with low-frequency neuronal coupling being the key driver of these changes.

Developmental excitation-inhibition imbalance permanently reprograms autism-relevant social brain circuits

This study shows that a transient developmental excitation-inhibition imbalance causes lasting social brain circuit dysfunction in mice, with behavioral and transcriptional consequences.

Synaptic-dependent developmental dysconnectivity in 22q11.2 deletion syndrome

This study investigates developmental dysconnectivity in 22q11.2 deletion syndrome using a cross-species approach, finding age-specific fMRI connectivity changes with synaptic origins.

Biological subtyping of autism via cross-species fMRI

The paper identifies hypo- and hyperconnectivity subtypes in autism using cross-species fMRI, linking them to distinct biological mechanisms in mice and humans.

Sex-biasing influence of autism-associated Ube3a gene overdosage at connectomic, behavioral and transcriptomic levels

This study shows that Ube3a gene overdosage causes sex-biased effects on brain connectivity, behavior, and gene expression in mice, linking it to autism-related phenotypes.

Unique spatiotemporal fMRI dynamics in the awake mouse brain

This study investigates spatiotemporal dynamics of spontaneous brain activity in awake mice using resting-state fMRI, finding unique patterns distinct from anesthetized states.

α-synuclein in the retina leads to degeneration of dopamine amacrine cells impairing vision

This study shows that overexpressing α-synuclein in the retina causes dopamine amacrine cell loss and visual impairment, which can be rescued by L-DOPA.