Cytoskeleton mechanics determine resting size and activation dynamics of platelets.
Aastha Mathur, Sandra Raquel Correia, Serge Dmitrieff, Romain Gibeaux, Iana Kalinina, Tooba Quidwai, Jonas Ries, Francois Nedelec
This study shows that platelet size is linked to microtubule content and that actin-driven coiling of the marginal band occurs during activation, with larger platelets showing greater coiling propensity.
bioRxiv · Sep 10, 2018 · PreprintCell Biology