Cornelia de Lange Syndrome-associated mutations in Smc1 cause both sister chromatid cohesion and cohesion-independent defects
Jingrong Chen, Frank M. Wu, Dean Dawson, Susannah Rankin
The paper uses budding yeast to assess the impact of CdLS-associated Smc1 mutations on cohesin function, identifying two classes of mutations with distinct effects on chromosome segregation and cohesion.
bioRxiv · Feb 10, 2018 · PreprintGenetics