Probiotic Associated Therapeutic Curli Hybrids (PATCH)
Pichet Praveschotinunt, Anna M. Duraj-Thatte, Ilia Gelfat, Franziska Bahl, David B. Chou, Neel S. Joshi
This study genetically engineers Escherichia coli to produce an anti-inflammatory matrix of curli nanofibers fused with trefoil factors, showing protective effects against colitis in mice.
bioRxiv · Nov 7, 2018 · PreprintBioengineering