The bromodomain protein Bdf3 is sufficient to activate expression of a procyclin gene in bloodstream stage African trypanosomes
Evan J Kim, Ethan L Goroza, Ashley Y Tan, Jolyne J Lin, Kieran Saucedo, Fuminori Tanizawa, Jaclyn E. Smith, Danae Schulz
This paper shows that Bdf3 activation at the EP promoter in bloodstream Trypanosoma brucei increases EP1 transcript levels, supporting its role in initiating transcription during differentiation to the procyclic stage.
mSphere · Jun 1, 2026Peer-reviewedMolecular Biology