Diffusional and chemical control in the tyrosine kinase network of platelet CLEC-2 signalling
A. A. Martyanov, Fyodor A Balabin, Joanne L. Dunster, Mikhail Aleksandrovich Panteleev, Jonathan M. Gibbins, Anastasia N. Sveshnikova
The paper develops a computational model of CLEC-2 signaling and validates its predictions experimentally, revealing temperature-dependent activation and lipid raft involvement.
bioRxiv · Jan 24, 2019 · PreprintSystems Biology