Jonathan M. Gibbins

Extended Modelling of Platelet Calcium Signaling by Combined Recurrent Neural Network and Partial Least Squares Analyses

This study models platelet calcium signaling using recurrent neural networks and partial least squares to predict and interpret calcium response patterns under various agonist conditions.

Evidence for direct control of neurovascular function by circulating platelets in healthy older adults

This study shows a direct link between platelet reactivity and neurovascular function in older adults, independent of vascular reactivity, suggesting a novel mechanism in early dementia pathophysiology.

Diffusional and chemical control in the tyrosine kinase network of platelet CLEC-2 signalling

The paper develops a computational model of CLEC-2 signaling and validates its predictions experimentally, revealing temperature-dependent activation and lipid raft involvement.