Cell BiologybioRxiv
The phosphatase PTPRG controls FGFR1 activity and influences sensitivity to FGFR kinase inhibitors
J. Wesche, M. Kostas, E. M. Haugsten…·A. Wiedlocha
The paper identifies PTPRG as a phosphatase that dephosphorylates FGFR1, enhancing FGFR inhibitor sensitivity in osteosarcoma cells.
DOI 10.1074/mcp.ra117.000538