RNA splicing alterations induce a cellular stress response associated with poor prognosis in AML
G. Anande, N. P. Deshpande, S. Mareschal, A. M. N. Batcha, H. R. Hampton, T. Herold, S. Lehmann, M. R. Wilkins, J. W. H. Wong, A. Unnikrishnan, J. E. Pimanda
The paper identifies RNA splicing alterations in AML patients without splicing factor mutations, linking them to stress response and poor prognosis through machine learning.
bioRxiv · Jan 10, 2020Cancer Biology