Author

J. E. Pimanda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Unnikrishnan· 2 shared D. Beck· 2 shared D. Chacon· 2 shared F. Zanini· 2 shared H. R. Hampton· 2 shared J. A. I. Thoms· 2 shared J. W. H. Wong· 2 shared S. Subramanian· 2 shared

Activity by Year

2020-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

A. Unnikrishnan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Single cell genotyping of matched bone marrow and peripheral blood cells in treatment naive and AZA-treated MDS and CMML

A. Schnegg-Kaufmann, J. A. I. Thoms, G. S. Bhuyan, H. R. Hampton, L. Vaughan, K. Rutherford, P. M. Kakadia, E. M. V. Johansson, T. Failes, G. M. Arndt, J. Koval, R. Lindeman, P. Warbuton, A. Rodriguez-Meira, A. J. Mead, , J. E. Pimanda

This study examines the contribution of mutated hematopoietic stem and progenitor cells to blood cell populations in MDS and CMML before and after AZA treatment.

bioRxiv · Jan 20, 2022 · PreprintCancer Biology

Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells

J. A. Thoms, K. Knezevic, G. Harvey, Y. Huang, J. Seneviratne, D. R. Carter, S. Subramanian, J. Skhinas, D. Chacon, A. Shah, I. de Jong, D. Beck, B. Gottgens, J. Larsson, J. W. Wong, , J. E. Pimanda

The paper identifies a GATA2, TAL1, ERG regulatory circuit that promotes erythroid transition in both healthy and leukemic stem cells, showing its persistence in AML with minor alterations.

bioRxiv · Oct 26, 2020Cancer Biology

Capturing Neonatal Cardiomyocyte - Endothelial interactions on-a-Chip

H. Tavassoli, Y. C. Kang, P. Rorimpandey, J. E. Pimanda, V. Chandrakanthan, P. P. Y. Chan

This study develops a microchip system to culture neonatal cardiomyocytes and endothelial cells, revealing migratory behaviors and interactions that may inform tissue engineering and drug discovery.

bioRxiv · Aug 10, 2020 · PreprintBioengineering

Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine.

A. Yeola, S. Subramanian, R. A. Oliver, C. A. Lucas, J. A. I. Thoms, F. Yan, J. Olivier, D. Chacon, M. L. Tursky, T. Hung, C. Power, P. Hardy, D. D. Ma, J. McCarroll, M. Kavallaris, , J. E. Pimanda

This study reprograms human adipocytes into induced multipotent stem cells using PDGF-AB and 5-Azacytidine, showing their ability to regenerate tissues without ectopic growth.

bioRxiv · Jun 4, 2020Cell Biology

RNA splicing alterations induce a cellular stress response associated with poor prognosis in AML

G. Anande, N. P. Deshpande, S. Mareschal, A. M. N. Batcha, H. R. Hampton, T. Herold, S. Lehmann, M. R. Wilkins, J. W. H. Wong, A. Unnikrishnan, J. E. Pimanda

The paper identifies RNA splicing alterations in AML patients without splicing factor mutations, linking them to stress response and poor prognosis through machine learning.

bioRxiv · Jan 10, 2020Cancer Biology