M. R. Wilkins

Cross-linking mass spectrometry discovers, evaluates, and validates the experimental and predicted structural proteome

The paper combines cross-linking mass spectrometry with AI-based structure prediction to discover and validate protein and complex structures at proteome scale.

Evidence for a putative isoprene reductase in Acetobacterium wieringae

This study identifies a putative isoprene reductase in Acetobacterium wieringae through proteogenomic analysis of an isoprene-reducing enrichment culture.

Long non-coding RNA RGMB-AS1 as a novel modulator of Bone Morphogenetic Protein Receptor 2 signaling in pulmonary arterial hypertension

This study identifies RGMB-AS1 as an upregulated lncRNA in PAH that modulates BMPR2 signaling and improves vascular cell function when inhibited.

Genomic insights into the Archaea inhabiting an Australian radioactive legacy site

This paper identifies and characterizes new archaeal taxa from a radioactive site using genome-based metagenomics, revealing their metabolic capabilities and evolutionary history.

One step forward, two steps back: transcriptional advancements and fermentation phenomena in Actinobacillus succinogenes 130Z

This paper develops a synthetic biology toolkit for Actinobacillus succinogenes 130Z but also highlights unexpected fermentation behavior changes over time.

Analysis of female song provides insight into the evolution of sex differences in a widely studied songbird

The paper analyzes female song in barn swallows to explore sex differences in phenotypic traits and their association with reproductive success, finding that female song traits show greater sexual differentiation than plumage traits.

Role of endothelial microRNA-150 in pulmonary arterial hypertension

This study shows that endothelial miR-150 protects against pulmonary arterial hypertension by regulating PTPMT1 and cardiolipin synthesis, reducing inflammation and apoptosis.

RNA splicing alterations induce a cellular stress response associated with poor prognosis in AML

The paper identifies RNA splicing alterations in AML patients without splicing factor mutations, linking them to stress response and poor prognosis through machine learning.

Migratory divides coincide with species barriers across replicated avian hybrid zones above the Tibetan Plateau

The paper examines reproductive isolation in barn swallow subspecies pairs, finding strong isolation coincides with migratory divides across the Tibetan Plateau, supporting the role of migratory behavior in speciation.

Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

This study identifies KLF2-induced microRNAs that protect endothelial cells and reduce pulmonary hypertension in animal models and patient samples.