Author

G. Bottegoni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Small· 1 shared C. J. McCabe· 1 shared C. M. Gorvin· 1 shared C. M. Thornton· 1 shared E. Rosta· 1 shared G. Mandana· 1 shared H. Adcock· 1 shared H. R. Nieto· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

B. Small

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2 papers

Recent·Most cited

Dual agonism of sodium iodide symporter function in vivo

K. Brookes, C. M. Thornton, L. Zha, J. Kim, B. Small, S. Manivannan, H. R. Nieto, H. Adcock, G. Bottegoni, L. R. Cox, V. Kannappan, W. Wang, C. M. Gorvin, S. Jhiang, M. D. Ringel, , C. J. McCabe

This study identifies Cu(DDC)2-alb as a dual agonist that enhances RAI uptake in thyroid cancer by stabilizing NIS and inducing thyroid transcription factors.

bioRxiv · Feb 27, 2024 · PreprintCancer Biology

Investigating the Unbinding of Muscarinic Antagonists from the Muscarinic 3 Receptor.

P. J. Buigues, S. Gehrke, M. Badaoui, G. Mandana, T. Qi, G. Bottegoni, E. Rosta

This paper investigates the unbinding mechanism of muscarinic antagonists from hMR3, identifying structural bottlenecks and key residues involved in the process.

bioRxiv · Jan 3, 2023Biophysics