Cooperation between MYC and β-catenin in liver tumorigenesis requires Yap/Taz
A. Bisso, M. Filipuzzi, G. P. Gamarra Figueroa, G. Brumana, F. Biagioni, M. Doni, G. Ceccotti, N. Tanaskovic, M. J. Morelli, V. Pendino, F. Chiacchiera, D. Pasini, D. Olivero, S. Campaner, A. Sabo, B. Amati
This study shows that Yap/Taz mediate the cooperation between MYC and β-catenin in liver tumorigenesis, identifying a prognostically significant gene signature in human hepatocellular carcinomas.
bioRxiv · Oct 25, 2019Cancer Biology